KMID : 1007520140230010313
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Food Science and Biotechnology 2014 Volume.23 No. 1 p.313 ~ p.322
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Antioxidant, Anti-inflammatory and Acetylcholinesterase Inhibitory Activities of Propolis from Different Regions of Morocco
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Maria da Graca Miguel
Orsula Doughmi Smail Aazza Dulce Antunes Badiaa Lyoussi
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Abstract
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Propolis is a bee product used since ancienttimes in folk medicine. Antioxidant activity is one of theproperties attributed to this natural product, which variesdepending on the botanical and geographic origin. Theantioxidant capacities of propolis from different regions ofMorocco were determined. Samples from the Khamissatand Immouzzer regions showed the highest antioxidantactivities (ABTS assay), reducing power, and peroxyl andhydroxyl radical scavenging capacities. The best capacitiesto inhibit 5-lipoxygenase were found in propolis samplesfrom Rabat. A strong correlation was found between theamounts of phenols, flavonoids, and antioxidant and antiinflammatoryactivities. These results support the hypothesisthat phenols contribute greatly to the pharma-cologicalproperties of propolis and suggest that propolis could beimportant in prevention of diseases in which free radicalsare implicated.
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KEYWORD
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Moroccan propolis, phenolic compounds, antioxydant activity, acetylcholinesterase
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