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KMID : 1007520140230010313
Food Science and Biotechnology
2014 Volume.23 No. 1 p.313 ~ p.322
Antioxidant, Anti-inflammatory and Acetylcholinesterase Inhibitory Activities of Propolis from Different Regions of Morocco
Maria da Graca Miguel

Orsula Doughmi
Smail Aazza
Dulce Antunes
Badiaa Lyoussi
Abstract
Propolis is a bee product used since ancienttimes in folk medicine. Antioxidant activity is one of theproperties attributed to this natural product, which variesdepending on the botanical and geographic origin. Theantioxidant capacities of propolis from different regions ofMorocco were determined. Samples from the Khamissatand Immouzzer regions showed the highest antioxidantactivities (ABTS assay), reducing power, and peroxyl andhydroxyl radical scavenging capacities. The best capacitiesto inhibit 5-lipoxygenase were found in propolis samplesfrom Rabat. A strong correlation was found between theamounts of phenols, flavonoids, and antioxidant and antiinflammatoryactivities. These results support the hypothesisthat phenols contribute greatly to the pharma-cologicalproperties of propolis and suggest that propolis could beimportant in prevention of diseases in which free radicalsare implicated.
KEYWORD
Moroccan propolis, phenolic compounds, antioxydant activity, acetylcholinesterase
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